专利名称：Neocarzinostatin derivatives and method of
producing the same
发明人：Maeda, Hiroshi,Kanamaru, Ryunosuke,Ishida,
Nakao,Yoshitake, Toshihiko,Ueda, Minoru
申请号：EP84305413.1申请日：19840808公开号：EP0136791A2公开日：19850410
摘要：Neocarzinostatin derivatives, having anticancer activity. have the formula (A)wherein (NCS) represents a divalent neocarzinostatin residue in which a hydrogen atom isremoved from each of the primary amino groups of the alanine residue at the N-terminalof neocarzinostatin and of the primary amino group of the lysine residue at the 20thposition from the N-terminal of neocarzinostatin and (SMA) represents a monovalentpartially half-esterified styrene-maleic acid copolymer residue having a weight-averagemolecular weight of 800 to 2,500 and consisting of structural units of
申请人：KURARAY CO., LTD.,YAMANOUCHI PHARMACEUTICAL CO. LTD.,KabushikiKaisha Kayaku (also trading as Kayaku Antibiotics Research Co. Ltd.),Maeda, Hiroshi
地址：1621 Sakazu Kurashiki-City Okayama Prefecture 710 JP,No. 5-1 Nihonbashi-Honcho, 2-chome Chuo-ku Tokyo JP,8-16 Funado, 2-Chome Itabashi-ku Tokyo JP,631-3,Aza-Tamukae Hotakubohon-Machi Kumamoto City Kumamoto Pref. JP
国籍：JP,JP,JP,JP
代理机构：Woods, Geoffrey Corlett
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