专利名称：Immunoassay for the detection of
procalcitonin
发明人：Joachim Struck申请号：US15412648申请日：20170123公开号：US10048280B2公开日：20180814
摘要：The present invention relates to an in vitro method for the detection ofProcalcitonin or a fragment thereof of at least 20 amino acid residues in length in abiological sample derived from a bodily fluid obtained from a subject, comprising thesteps of: (i) contacting said sample with at least two antibodies or functional fragmentsthereof directed against different epitopes within Procalcitonin, and (ii) qualitatively orquantitatively detecting binding of said at least two antibodies to Procalcitonin or saidfragment thereof, wherein binding indicates the presence or concentration of
Procalcitonin or said fragment in said sample, wherein at least one antibody or functionalfragment thereof is directed against an epitope comprised in the sequence spanningamino acid residues 2 to 52 of Procalcitonin. The invention also pertains to antibodiesdirected against an N-terminal epitope of Procalcitonin and kits comprising antibodiesdirected against PCT.
申请人：B.R.A.H.M.S GMBH
地址：Henningsdorf DE
国籍：DE
代理机构：Millen White Zelano & Branigan, PC
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